Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435420 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL6435427 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL14707759 | 0.80 | ASAH1 (0.38) | KCNK3ALDH1A1THRBCNR2BLM | |
| SCHEMBL14707758 | 0.80 | ASAH1 (0.38) | KCNK3ALDH1A1THRBCNR2BLM | |
| SCHEMBL4348828 | 0.80 | KCNK3 (0.34) | KCNK3ALDH1A1THRBCNR2BLM | |
| SCHEMBL13887653 | 0.80 | ASAH1 (0.38) | KCNK3ALDH1A1THRBCNR2BLM | |
| SCHEMBL7956648 | 0.78 | SIGMAR1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19CA1 | |
| SCHEMBL7956652 | 0.78 | SIGMAR1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19CA1 | |
| SCHEMBL7586491 | 0.76 | TDP1 (0.39) | TDP1CA1CA2CNR1MMP1 | |
| SCHEMBL20669502 | 0.76 | TDP1 (0.39) | TDP1CA1CA2CNR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957114-B1 | Azoamide compounds and their use as polymerisation initiators | WAKO PURE CHEM IND LTD (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6031084-A | Azoamide compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| EP-0957114-A1 | Azoamide compounds and their use as polymerisation initiators | Wako Pure Chemical Industries, Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |