Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574476 | 1.00 | MAPT (0.36) | MAPTPOLBRAB9ALMNAKMT2A | |
| SCHEMBL7580530 | 0.87 | MAPT (0.37) | MAPTPOLBRAB9ALMNAKMT2A | |
| SCHEMBL7580524 | 0.87 | MAPT (0.37) | MAPTPOLBRAB9ALMNAKMT2A | |
| SCHEMBL7575432 | 0.86 | KMT2A (0.38) | MAPTPOLBLMNAKMT2AHTT | |
| SCHEMBL7575438 | 0.86 | KMT2A (0.38) | MAPTPOLBLMNAKMT2AHTT | |
| SCHEMBL7574920 | 0.81 | ALDH1A1 (0.40) | MAPTPOLBRAB9ALMNAKMT2A | |
| SCHEMBL7575413 | 0.81 | NFE2L2 (0.35) | MAPTRAB9ALMNAKMT2AHTT | |
| SCHEMBL7574921 | 0.81 | ALDH1A1 (0.40) | MAPTPOLBRAB9ALMNAKMT2A | |
| SCHEMBL7575405 | 0.81 | NFE2L2 (0.35) | MAPTRAB9ALMNAKMT2AHTT | |
| SCHEMBL7580233 | 0.79 | PARP15 (0.38) | POLBRAB9ALMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |