Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | AGT | P01019 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854720 | 0.81 | KMT2A (0.40) | GAAHPGDKDM4EALDH1A1TSHR | |
| SCHEMBL7572573 | 0.81 | SOAT1 (0.36) | AGTR1SOAT1GAAHPGDKDM4E | |
| SCHEMBL7565426 | 0.76 | AGTR1 (0.41) | AGTR1AGTR2SOAT1AGTTSHR | |
| SCHEMBL4735569 | 0.75 | SOAT1 (0.47) | AGTR1AGTR2SOAT1GAAHPGD | |
| SCHEMBL7575457 | 0.73 | SOAT1 (0.40) | AGTR1AGTR2SOAT1GAAHPGD | |
| SCHEMBL3948155 | 0.73 | LTB4R2 (0.57) | AGTR1AGTR2AGTGAAHPGD | |
| SCHEMBL9709733 | 0.71 | AGTR1 (0.39) | AGTR1AGTR2AGT | |
| SCHEMBL7567763 | 0.69 | POLB (0.49) | GAAHPGDKDM4EALDH1A1TSHR | |
| SCHEMBL9022990 | 0.67 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL9592378 | 0.67 | AGT (0.46) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |