Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948155 | 0.83 | LTB4R2 (0.57) | GAAMEN1POLBKMT2AAGTR1 | |
| SCHEMBL4672053 | 0.83 | AGTR1 (0.47) | SOAT1RAB9ANPC1AGTR1AGTR2 | |
| SCHEMBL4735565 | 0.82 | AGTR1 (0.45) | RAB9ANPC1MEN1POLBKMT2A | |
| SCHEMBL9262004 | 0.77 | AGTR1 (0.46) | GAAMEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL7565426 | 0.77 | AGTR1 (0.41) | SOAT1AGTR1AGTR2 | |
| SCHEMBL9022990 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL489527 | 0.77 | AGTR1 (0.49) | AGTR1AGTR2SMN1; SMN2LMNA | |
| SCHEMBL3950208 | 0.76 | AGTR1 (0.49) | AGTR1AGTR2SMN1; SMN2LMNA | |
| SCHEMBL3370402 | 0.76 | AGTR1 (0.46) | POLBAGTR1AGTR2HPGD | |
| SCHEMBL13679199 | 0.76 | AGTR1 (0.47) | POLBAGTR1AGTR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590343-B1 | SYNTHESIS OF 2-BUTYL-3-(2' -(1-TRITYL-1H-TETRAZOL-5-YL)BIPHEN YL-4-YL)-1,3-DIAZASPIRO-4,4 -NONENE-4-ONE | TEVA PHARMA (IL) | 2008-07-16 | — | — | EP | claimed |