Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575457 | 0.91 | SOAT1 (0.40) | SOAT1HPGDGAATSHRALDH1A1 | |
| SCHEMBL7575437 | 0.81 | AGTR1 (0.36) | SOAT1HPGDGAATSHRALDH1A1 | |
| SCHEMBL7575469 | 0.74 | BDKRB1 (0.44) | SOAT1LTB4R2BDKRB1GSK3AAGTR1 | |
| SCHEMBL7570385 | 0.74 | SOAT1 (0.40) | SOAT1HPGDGAATSHRALDH1A1 | |
| SCHEMBL7570389 | 0.74 | HTT (0.40) | SOAT1HPGDTSHRALDH1A1POLB | |
| SCHEMBL9263749 | 0.73 | AGTR1 (0.41) | SOAT1HSD17B10LTB4R2AGTR1MAPK1 | |
| SCHEMBL7570660 | 0.73 | PTGER1 (0.41) | SOAT1BDKRB1 | |
| SCHEMBL9479326 | 0.71 | AGTR1 (0.40) | SOAT1TSHRALDH1A1HSD17B10LTB4R2 | |
| SCHEMBL7567763 | 0.70 | POLB (0.49) | HPGDGAATSHRALDH1A1KDM4E | |
| SCHEMBL4609709 | 0.70 | LTB4R2 (0.60) | HPGDGAAALDH1A1POLBLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |