Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374750 | 0.84 | DRD2 (0.45) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL1229552 | 0.79 | CSNK2A2 (0.35) | ALDH1A1USP2LMNA | |
| SCHEMBL1537447 | 0.78 | — | — | |
| SCHEMBL18538874 | 0.78 | GNAI3 (0.58) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL2318272 | 0.78 | GNAI3 (0.58) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL1043894 | 0.78 | GNAI3 (0.58) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL26132063 | 0.76 | DRD2 (0.42) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL6659463 | 0.75 | GNAI3 (0.62) | GNAI3GNAO1GNAI1HRH3LMNA | |
| SCHEMBL6656715 | 0.75 | GNAI3 (0.56) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL6658199 | 0.75 | GNAI3 (0.56) | DRD2DRD3GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137590-B2 | Particles comprising zwitterionic structural elements | WACKER CHEMIE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20080286628-A1 | Particles Comprising Zwitterionic Structural Elements | WACKER CHEMIE AG (DE) | 2008-11-20 | — | — | US | disclosed |