Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095954 | 0.88 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL28226906 | 0.87 | ALDH1A1 (0.77) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL2090542 | 0.85 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8159579 | 0.84 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL6926448 | 0.84 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL11465528 | 0.84 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL2090423 | 0.84 | SIGMAR1 (0.71) | SIGMAR1ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8577276 | 0.84 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| Hydrochloric Acid SCHEMBL10997933 | 0.82 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL7295918 | 0.82 | ALDH1A1 (0.66) | SIGMAR1ALDH1A1HTR3EHTR3BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200408-A | Urea or thiourea derivatives; pain treatment | LABORATOIRES UPSA (FR) | 1993-04-06 | — | — | US | claimed |
| EP-0195374-B1 | N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND COMPOSITION CONTAINING SAME FOR TREATING DISORDERS OF CARDIOVASCULAR SYSTEM | SUNTORY LIMITED (JP) | 1992-07-29 | — | — | EP | claimed |
| CN-102125557-A | Use of flibanserin in the treatment of sexual disorders | BOEHRINGER INGELHEIM PHARMA | 2011-07-20 | — | — | CN | disclosed |
| CN-102058597-A | Use of flibanserin in the treatment of sexual disorders | BOEHRINGER INGELHEIM PHARMA | 2011-05-18 | — | — | CN | disclosed |
| CN-101347431-A | Use of flibanserin in the treatment of sexual disorders | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-01-21 | — | — | CN | disclosed |
| CN-1946404-A | Pharmaceutical compositions for the treatment of sexual disorders II | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-04-11 | — | — | CN | disclosed |
| CN-1571670-A | Use of flibanserin in the treatment of sexual disorders | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-01-26 | — | — | CN | disclosed |
| WO-2002092088-A2 | NOVEL USE OF 2H-BENZIMIDAZOL-2-ONE, 1,3-DIHADRO-1-(2{4-{3-(TRIFLUOROMETHYL}PHENYL]-1-PIPERAZINYL}ETHYL)- AND ITS PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS | BECK JUERGEN K (DE) | 2002-11-21 | — | — | WO | disclosed |
| US-5200408-A | Urea or thiourea derivatives; pain treatment | LABORATOIRES UPSA (FR) | 1993-04-06 | — | — | US | disclosed |
| EP-0195374-B1 | N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND COMPOSITION CONTAINING SAME FOR TREATING DISORDERS OF CARDIOVASCULAR SYSTEM | SUNTORY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4017623-A | Esters of 2-[(4-quinolyl)amino]-benzoic acids in analgesic and anti-inflammatory compositions | SYNTHELABO (FR) | 1977-04-12 | — | — | US | disclosed |