Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10997933 | 0.99 | SIGMAR1 (0.59) | SIGMAR1LMNASMN1; SMN2MAPK1RECQL | |
| SCHEMBL1733940 | 0.86 | SIGMAR1 (0.60) | SIGMAR1LMNASMN1; SMN2MAPK1RAB9A | |
| SCHEMBL7575596 | 0.84 | SIGMAR1 (0.64) | SIGMAR1LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL28226906 | 0.83 | ALDH1A1 (0.77) | SIGMAR1LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8560489 | 0.82 | SIGMAR1 (0.56) | SIGMAR1LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL8560485 | 0.82 | SIGMAR1 (0.56) | SIGMAR1LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL2095954 | 0.81 | SIGMAR1 (0.69) | SIGMAR1SMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL8159579 | 0.81 | SIGMAR1 (0.64) | SIGMAR1LMNASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL11465528 | 0.81 | SIGMAR1 (0.76) | SIGMAR1SMN1; SMN2MAPK1ALDH1A1MAPT | |
| SCHEMBL6926448 | 0.81 | SIGMAR1 (0.64) | SIGMAR1LMNASMN1; SMN2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015541-A1 | NOVEL ISOXAZOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1998-04-16 | — | — | WO | disclosed |