Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615254 | 0.87 | PDE10A (0.36) | PDE10AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL27596540 | 0.83 | CNR2 (0.40) | PDE10AKMT2AMEN1ADORA1KDM4E | |
| SCHEMBL24809118 | 0.81 | DGAT1 (0.40) | DGAT1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4312796 | 0.78 | DGAT1 (0.43) | DGAT1KDM4ETSHRNPC1MAPT | |
| SCHEMBL2030421 | 0.77 | DGAT1 (0.43) | DGAT1NPC1MAPT | |
| SCHEMBL20163415 | 0.77 | DGAT1 (0.47) | DGAT1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3355074 | 0.77 | DGAT1 (0.43) | DGAT1NPC1MAPT | |
| SCHEMBL23783005 | 0.77 | DGAT1 (0.40) | DGAT1KMT2AMEN1NPC1 | |
| SCHEMBL28730648 | 0.76 | DGAT1 (0.42) | DGAT1NPC1MAPT | |
| SCHEMBL23042316 | 0.76 | DGAT1 (0.44) | DGAT1KMT2AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053345-A1 | Indazole Compounds | ABBOTT LABORATORIES (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053345-A1 | Indazole Compounds | CYP3A43, CYP3A7, UGT1A1 | DGAT1 2137/4885PDE10A 1123/4885KMT2A 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.