Oxyfluorfen

Oxyfluorfen

SCHEMBL7575869

CC1(C)OC(c2ccco2)CN1C(=O)C(Cl)Cl.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TTR P02766 1/20 0.30
PPOX P50336 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7580844 0.96 LMNA (0.30) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Acifluorfen SCHEMBL7581058 0.95 MEN1 (0.37) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7582455 0.94 MEN1 (0.33) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Fomesafen SCHEMBL7583114 0.93 MEN1 (0.32) MEN1KMT2ATTRPPOXTDP1
Lactofen SCHEMBL7588012 0.92 MEN1 (0.32) MEN1KMT2ATTRPPOXTDP1
Metolachor SCHEMBL7587786 0.92 MEN1 (0.32) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7586959 0.91 TDP1 (0.31) MEN1KMT2AALDH1A1TTRPPOX
Oxyfluorfen SCHEMBL7588210 0.91 MEN1 (0.32) LMNASMN1; SMN2MEN1KMT2ATTR
Acifluorfen SCHEMBL7578933 0.91 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7587106 0.90 MEN1 (0.30) MEN1KMT2ATTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885SMN1; SMN2 4618/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.