Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | S100A9 | P06702 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140163 | 1.00 | CYP3A4 (0.46) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL11298945 | 0.86 | CYP3A4 (0.45) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL22815715 | 0.85 | KMO (0.47) | CYP3A4TSHRSLC1A5KMOGRIN2B | |
| SCHEMBL1555931 | 0.84 | CYP3A4 (0.46) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL9447561 | 0.83 | MEN1 (0.44) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL27483990 | 0.83 | CYP3A4 (0.42) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL3802892 | 0.82 | CYP3A4 (0.48) | CYP3A4TSHRCA1CA2MRGPRX4 | |
| SCHEMBL9367414 | 0.81 | GAA (0.40) | CYP3A4TSHRSCN9AALDH1A1ALOX15 | |
| SCHEMBL28351619 | 0.80 | MEN1 (0.42) | CYP3A4TSHRSLC1A5CA1CA2 | |
| SCHEMBL11307249 | 0.80 | CYP3A4 (0.39) | CYP3A4TSHRSLC1A5CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) | 2025-06-24 | — | — | US | disclosed |
| CN-116768824-B | Imide azole heterocyclic compound and application thereof | 华南农业大学 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-119241440-A | Indazole benzoic acid derivative containing urea structure and preparation method and application thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| US-20240376117-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-11-14 | — | — | US | disclosed |
| WO-2024141128-A4 | STING INHIBITOR PRODRUG AND MEDICAL USE THEREOF | 中国药科大学 | 2024-09-19 | — | — | WO | disclosed |
| US-20240287020-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2024-08-29 | — | — | US | disclosed |
| US-12054492-B2 | Imidazole-containing inhibitors of ALK2 kinase | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| WO-2024151666-A1 | CARBOXYLIC ACID ANALOGS AS GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-4293566-A | FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| EP-0003099-B1 | N-PHENYL-N'(2-CHLORO-6-FLUORO-BENZOYL) UREA, PREPARATION THEREOF AND USE THEREOF AS INSECTICIDES | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4277499-A | Combating insects with N-(substituted-phenyl)-N-(2-chloro-6-fluoro-benzoyl)-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| US-4276310-A | ARTHROPODICIDES, FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-30 | — | — | US | disclosed |
| EP-0000156-B1 | 2-ARYLAMINO-3,5-DINITRO-BENZOTRIFLUORIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES. | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| US-4233055-A | Quaternary ammonioalkanecarboxylic acid anilides as plant growth influencing agents | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4183949-A | Pesticidally active 1-arylamino-2,4-dinitronaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4141718-A | ANTIGROWTH AGENTS FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4139636-A | N-Phenyl-N'-benzoyl-ureas and pesticidal compositions and uses therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
| EP-0000156-A1 | 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376117-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | ALK, ACVR2B, ACVR2A | CYP3A4 3136/4885TSHR 3668/4885SLC1A5 1358/4885 |
| US-12054492-B2 | Imidazole-containing inhibitors of ALK2 kinase | ALK, ACVR2B, ACVR2A | CYP3A4 3136/4885TSHR 3668/4885SLC1A5 1358/4885 |
| US-20240287020-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | XDH, CYP11B2, CYP4X1 | CYP3A4 10/4885TSHR 1665/4885SLC1A5 464/4885 |
| US-12338226-B2 | Substituted benzodiazoles and use thereof in therapy | XDH, CYP11B2, CYP4X1 | CYP3A4 10/4885TSHR 1665/4885SLC1A5 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.