Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572253 | 0.82 | CYP3A4 (0.46) | PDE3AALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL7573073 | 0.82 | KDM4E (0.39) | ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL7580611 | 0.80 | MAPT (0.44) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL7573743 | 0.80 | MAPT (0.41) | PDE3AALDH1A1HPGDMAPTKDM4E | |
| Dimethylamine SCHEMBL7572333 | 0.79 | KDM4E (0.39) | ALDH1A1HPGDMAPTKDM4EFLT4 | |
| SCHEMBL7575694 | 0.79 | CNR2 (0.39) | ALDH1A1HPGDMAPTGAACNR2 | |
| SCHEMBL7572329 | 0.78 | PIM1 (0.41) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL7574674 | 0.78 | KDM4E (0.41) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL7573733 | 0.76 | GRM2 (0.41) | HPGDKDM4EADORA1NPSR1LRRK2 | |
| SCHEMBL7575492 | 0.76 | RARB (0.55) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |