Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | IL2 | P60568 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126994 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1RAB9AMAPTL3MBTL1HCRTR1 | |
| SCHEMBL15999077 | 0.78 | PDK2 (0.44) | ALDH1A1PDK2CA12CA1CA2 | |
| SCHEMBL536163 | 0.78 | S1PR3 (0.51) | ALDH1A1LMNAMAPTCA12CA1 | |
| SCHEMBL8155327 | 0.78 | PTGS2 (0.54) | ALDH1A1RAB9AMAPTL3MBTL1PDK2 | |
| SCHEMBL31156224 | 0.78 | ADORA2A (0.42) | ALDH1A1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL31743276 | 0.78 | ADORA2A (0.42) | ALDH1A1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL7569920 | 0.77 | TDP1 (0.53) | ALDH1A1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL31155957 | 0.76 | LMNA (0.45) | ALDH1A1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL31156307 | 0.75 | ALDH1A1 (0.52) | ALDH1A1LMNAADORA2AXDHTDP1 | |
| SCHEMBL2478176 | 0.75 | CA1 (0.49) | ALDH1A1LMNAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | ALDH1A1 385/4885RAB9A 1816/4885LMNA 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.