SCHEMBL7576499

SCHEMBL7576499

N#CCCc1ccn[c]c1-c1ccccc1O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.31
IDO1 P14902 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7576190 0.82 IDO1 (0.38) SMN1; SMN2IDO1
SCHEMBL2162646 0.69 TAAR1 (0.54) IDO1MEN1KMT2A
SCHEMBL7570634 0.69 SMN1; SMN2 (0.40) SMN1; SMN2IDO1MEN1KMT2A
SCHEMBL8473218 0.68 HPGD (0.53) SMN1; SMN2IDO1MEN1KMT2A
SCHEMBL7572110 0.65 KDM1A (0.40) SMN1; SMN2
SCHEMBL8764227 0.63 MEN1 (0.52) MEN1KMT2A
SCHEMBL11681257 0.62 MEN1 (0.44) IKBKBIDO1MEN1KMT2A
SCHEMBL9442560 0.61 CSNK1A1 (0.43) IDO1MEN1KMT2A
SCHEMBL10533398 0.61 KEAP1 (0.53) IDO1MEN1KMT2A
SCHEMBL9284366 0.60 DPP4 (0.50) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002089799-A2 USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed