Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473218 | 0.77 | HPGD (0.53) | SMN1; SMN2ALDH1A1KMT2AHSD17B10IDO1 | |
| SCHEMBL7572110 | 0.73 | KDM1A (0.40) | SMN1; SMN2ALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL7576190 | 0.73 | IDO1 (0.38) | SMN1; SMN2ALDH1A1MAPK1HSD17B10IDO1 | |
| SCHEMBL7576499 | 0.69 | IKBKB (0.34) | SMN1; SMN2KMT2AIDO1MEN1 | |
| SCHEMBL3751745 | 0.68 | IDO1 (0.41) | SMN1; SMN2ALDH1A1KMT2AMAPK1HSD17B10 | |
| SCHEMBL26104342 | 0.68 | CYP17A1 (0.48) | SMN1; SMN2KMT2AIDO1HPGDMAPT | |
| SCHEMBL1854469 | 0.68 | — | — | |
| SCHEMBL10439544 | 0.66 | MAPK1 (0.61) | SMN1; SMN2ALDH1A1KMT2AMAPK1HSD17B10 | |
| SCHEMBL3751748 | 0.66 | BACE1 (0.38) | SMN1; SMN2ALDH1A1KMT2AMAPK1HSD17B10 | |
| SCHEMBL10034853 | 0.66 | MAPK1 (0.61) | SMN1; SMN2ALDH1A1KMT2AMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089799-A2 | USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |