Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457109 | 0.84 | CRBN (0.51) | CRBNDDB1GAAUPP1MCL1 | |
| SCHEMBL2709043 | 0.73 | CRBN (0.56) | CRBNDDB1GAAL3MBTL1KDM4E | |
| SCHEMBL27732654 | 0.67 | CRBN (0.49) | CRBNDDB1GAAKDM4ELMNA | |
| SCHEMBL2423501 | 0.67 | TSHR (0.46) | GAAMAP2K1MCL1KDM4ELMNA | |
| SCHEMBL8018395 | 0.66 | CRBN (0.56) | CRBNDDB1KDM4EALDH1A1MAPT | |
| SCHEMBL25565848 | 0.66 | CRBN (0.56) | CRBNDDB1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6557227 | 0.66 | CRBN (0.56) | CRBNDDB1GAAKDM4EALDH1A1 | |
| SCHEMBL6406005 | 0.66 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL7401686 | 0.66 | MCL1 (0.44) | MCL1L3MBTL1KDM4EKMT2ACA1 | |
| SCHEMBL23296167 | 0.65 | CRBN (0.65) | CRBNDDB1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942905-B1 | 3-AMINO-1-CYANOPHENYL-URACILS | BAYER AG (DE) | 2002-02-20 | — | — | EP | claimed |