Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.56 |
| ▸ | HCAR1 | Q9BXC0 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242299 | 0.79 | CRBN (0.53) | CRBNDDB1HCAR1ALDH1A1KMT2A | |
| SCHEMBL6557227 | 0.78 | CRBN (0.56) | CRBNDDB1HCAR1ALDH1A1POLB | |
| SCHEMBL10980130 | 0.78 | ALDH1A1 (0.64) | CRBNDDB1HCAR1ALDH1A1MGLL | |
| SCHEMBL2709043 | 0.78 | CRBN (0.56) | CRBNDDB1HCAR1ALDH1A1KMT2A | |
| SCHEMBL8018395 | 0.78 | CRBN (0.56) | CRBNDDB1HCAR1ALDH1A1MGLL | |
| SCHEMBL6406005 | 0.78 | CRBN (0.56) | CRBNDDB1HCAR1 | |
| SCHEMBL23121407 | 0.76 | ESR1 (0.46) | CRBNDDB1HCAR1ALDH1A1MAPT | |
| SCHEMBL7457109 | 0.74 | CRBN (0.51) | CRBNDDB1KMT2AMAPTMEN1 | |
| SCHEMBL23121039 | 0.74 | HTR3E (0.47) | CRBNDDB1HCAR1ALDH1A1KMT2A | |
| SCHEMBL7977829 | 0.73 | CRBN (0.50) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598875-A | Pyrimidine diketone amide compound and preparation method and application thereof | 广州医科大学 | 2024-09-06 | — | — | CN | disclosed |
| WO-2023096995-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED N-(2-CHLORO-6-METHYLPHENYL)-2-((6-(6-MEMBERED HETEROCYCLOALKYL)-2-METHYLPYRIMIDIN-4-YL)AMINO)THIAZOLE-5-CARBOXAMIDE ANALOGUES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| CN-114605408-A | 5-hydroxy-1, 3-disubstituted phenyl pyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-10 | — | — | CN | disclosed |