Bifenox

Bifenox

SCHEMBL7576717

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
TTR P02766 1/20 0.53
PPOX P50336 1/20 0.53
GABRP O00591 5/20 0.41
GABRD O14764 5/20 0.41
GABRA1 P14867 5/20 0.41
GABRB1 P18505 5/20 0.41
GABRG2 P18507 5/20 0.41
GABRB3 P28472 5/20 0.41
GABRA5 P31644 5/20 0.41
GABRA3 P34903 5/20 0.41
GABRA2 P47869 5/20 0.41
GABRB2 P47870 5/20 0.41
GABRA4 P48169 5/20 0.41
GABRE P78334 5/20 0.41
GABRA6 Q16445 5/20 0.41
GABRG1 Q8N1C3 5/20 0.41
GABRG3 Q99928 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop-Methyl SCHEMBL7587639 0.85 TDP1 (0.43) TDP1KMT2AMEN1TTRPPOX
SCHEMBL7586912 0.84 TDP1 (0.53) TDP1KMT2AMEN1TTRPPOX
Lactofen SCHEMBL7578463 0.83 TDP1 (0.51) TDP1KMT2AMEN1TTRPPOX
Acifluorfen SCHEMBL7027306 0.81 TDP1 (0.80) TDP1KMT2AMEN1TTRPPOX
Acifluorfen-Methyl SCHEMBL30749491 0.81 MEN1 (0.78) TDP1KMT2AMEN1TTRPPOX
Acifluorfen-Methyl SCHEMBL31614705 0.81 MEN1 (0.78) TDP1KMT2AMEN1TTRPPOX
Acifluorfen-Methyl SCHEMBL39092 0.81 MEN1 (0.78) TDP1KMT2AMEN1TTRPPOX
Acifluorfen SCHEMBL8562734 0.81 TDP1 (0.75) TDP1KMT2AMEN1TTRPPOX
Bifenox SCHEMBL30862569 0.80 TDP1 (1.00) TDP1KMT2AMEN1TTRPPOX
Bifenox SCHEMBL8541647 0.80 TDP1 (1.00) TDP1KMT2AMEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885KMT2A 2099/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.