Diclofop-Methyl

Diclofop-Methyl

SCHEMBL7587639

COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
PDE7A Q13946 1/20 0.36
GABRP O00591 3/20 0.36
GABRD O14764 3/20 0.36
GABRA1 P14867 3/20 0.36
GABRB1 P18505 3/20 0.36
GABRG2 P18507 3/20 0.36
GABRB3 P28472 3/20 0.36
GABRA5 P31644 3/20 0.36
GABRA3 P34903 3/20 0.36
GABRA2 P47869 3/20 0.36
GABRB2 P47870 3/20 0.36
GABRA4 P48169 3/20 0.36
GABRE P78334 3/20 0.36
GABRA6 Q16445 3/20 0.36
GABRG1 Q8N1C3 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop-Methyl SCHEMBL7586776 0.87 JMJD7 (0.36) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL7576717 0.85 TDP1 (0.64) TDP1MEN1KMT2ATTRPPOX
Mecoprop SCHEMBL7581550 0.80 TSHR (0.48) TDP1MEN1KMT2ATTRPPOX
SCHEMBL7585729 0.80 MEN1 (0.38) TDP1MEN1KMT2ATTRPPOX
Quizalofop SCHEMBL7581249 0.80 LMNA (0.47) TDP1MEN1KMT2ATTRPPOX
Clodinafop SCHEMBL7578921 0.79 SMN1; SMN2 (0.38) TDP1MEN1KMT2ATTRPPOX
Fluazifop SCHEMBL7583299 0.79 RAB9A (0.47) TDP1MEN1KMT2ATTRPPOX
Fenoxaprop SCHEMBL7588818 0.79 PPARG (0.34) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7583843 0.79 TDP1 (0.71) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7578463 0.78 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.