Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226510 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL1804845 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL2517959 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL4794837 | 1.00 | LPAR1 (0.58) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL1081182 | 0.90 | ALDH1A1 (0.53) | LPAR1LPAR3LPAR2 | |
| SCHEMBL303128 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL4204833 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL8636551 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL4879843 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL4294185 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2DNM1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113840624-A | Monosaccharide-labeled nanoliposome drug delivery system, preparation method thereof and application thereof as drug targeting delivery carrier | 法玛科技顾问股份有限公司 | 2021-12-24 | — | — | CN | claimed |
| WO-2020232701-A1 | MONOSACCHARIDE LABELED NANOLIPOSOME DRUG DELIVERY SYSTEM, PREPARATION METHOD THEREFOR AND USE OF SAME AS TARGETING DELIVERY VECTOR FOR DRUG | 法玛科技顾问股份有限公司 (CN) | 2020-11-26 | — | — | WO | claimed |
| EP-3673899-A1 | NASAL POWDER FORMULATION FOR TREATMENT OF HYPOGLYCEMIA | ELI LILLY AND CO. (US) | 2020-07-01 | — | — | EP | claimed |
| EP-3673900-A1 | NASAL POWDER FORMULATION FOR TREATMENT OF HYPOGLYCEMIA | ELI LILLY AND CO. (US) | 2020-07-01 | — | — | EP | claimed |
| US-20180104238-A9 | Method And Composition For Treating Rhinitis | BIOLIPOX AB (SE) | 2018-04-19 | — | — | US | claimed |
| US-20170202775-A1 | METHOD FOR PREPARATION OF LIPID BUBBLES | SOUTHEAST UNIVERSITY (CN) | 2017-07-20 | — | — | US | claimed |
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | claimed |
| EP-1919450-B1 | ANTIHISTAMINE- AND CORTICOSTEROID-CONTAINING LIPOSOME COMPOSITION AND ITS USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING RHINITIS AND RELATED DISORDERS | MEDA AB (SE) | 2014-06-11 | — | — | EP | claimed |
| US-20140065203-A1 | ANTIHISTAMINE- AND CORTICOSTEROID-CONTAINING LIPOSOME COMPOSITION AND ITS USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING RHINITIS AND RELATED DISORDERS | BIOLIPOX AB (SE) | 2014-03-06 | — | — | US | claimed |
| EP-1888033-B1 | METHOD AND COMPOSITION FOR TREATING INFLAMMATORY DISORDERS | MEDA AB (SE) | 2014-02-19 | — | — | EP | claimed |
| US-5874104-A | ALSO CONTAINING CHOLESTEROL; HYDRATED IN AQUEOUS MONO- OR DISACCHARIDE; STORAGE STABILITY | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-02-23 | — | — | US | claimed |
| US-5759571-A | AMINOGLYCOSIDE ENCAPSULATED IN LIPOSOMES OF CHOLESTEROL AND LIPIDS | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-06-02 | — | — | US | claimed |
| US-5756121-A | FORMING LIPOSOMES FOR TREATMENT OF DRUG RESISTANT BACTERIA | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | claimed |
| US-5756120-A | CONTAINING LIPID AND STEROL | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | claimed |
| US-5688525-A | LIPOSOMES AND LIPIDS WITH CHOLESTEROL AND CYCLOSPORIN | NEXSTAR PHARMACEUTICALS, INC. (US) | 1997-11-18 | — | — | US | claimed |
| EP-0580817-B1 | PHARMACEUTICAL FORMULATION AND PROCESS | NEXSTAR PHARMACEUTICALS INC (US) | 1996-06-19 | — | — | EP | claimed |
| EP-0580817-A1 | PHARMACEUTICAL FORMULATION AND PROCESS. | VESTAR INC (US) | 1994-02-02 | — | — | EP | claimed |
| WO-1992018104-A1 | PHARMACEUTICAL FORMULATION AND PROCESS | VESTAR, INC. (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0317120-B1 | IMPROVED AMPHOTERICIN B LIPOSOME PREPARATION | VESTAR, INC. (US) | 1991-08-28 | — | — | EP | claimed |
| EP-0317120-A1 | Improved amphotericin B liposome preparation | VESTAR, INC. (US) | 1989-05-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140065203-A1 | ANTIHISTAMINE- AND CORTICOSTEROID-CONTAINING LIPOSOME COMPOSITION AND ITS USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING RHINITIS AND RELATED DISORDERS | HRH1, HRH4, HRH3 | LPAR1 17/4885LPAR3 21/4885LPAR2 19/4885 |
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | LIPA, HRH2, HRH1 | LPAR1 42/4885LPAR3 51/4885LPAR2 31/4885 |
| US-20180104238-A9 | Method And Composition For Treating Rhinitis | HRH1, HRH2, LIPA | LPAR1 12/4885LPAR3 10/4885LPAR2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.