SCHEMBL226510

SCHEMBL226510

CCCCCCCCCCCCCCCCOCC(COP)OCCCCCCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 0.58
LPAR3 Q9UBY5 9/20 0.58
LPAR2 Q9HBW0 6/20 0.58
DNM1 Q05193 1/20 0.50
USP2 O75604 1/20 0.47
TLR2 O60603 4/20 0.47
HTT P42858 1/20 0.46
PRKD3 O94806 1/20 0.45
PRKCG P05129 1/20 0.45
PRKCB P05771 1/20 0.45
PRKCA P17252 1/20 0.45
PRKCH P24723 1/20 0.45
PRKCI P41743 1/20 0.45
PRKCE Q02156 1/20 0.45
PRKCQ Q04759 1/20 0.45
PRKCZ Q05513 1/20 0.45
PRKCD Q05655 1/20 0.45
PRKD1 Q15139 1/20 0.45
LPAR6 P43657 5/20 0.44
LPAR4 Q99677 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757679 1.00 LPAR1 (0.58) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL1804845 1.00 LPAR1 (0.58) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL2517959 1.00 LPAR1 (0.58) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL4794837 1.00 LPAR1 (0.58) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL1081182 0.90 ALDH1A1 (0.53) LPAR1LPAR3LPAR2
SCHEMBL303128 0.90 LPAR1 (0.68) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL4204833 0.90 LPAR1 (0.68) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL8636551 0.90 LPAR1 (0.68) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL4879843 0.90 LPAR1 (0.68) LPAR1LPAR3LPAR2DNM1USP2
SCHEMBL4294185 0.90 LPAR1 (0.68) LPAR1LPAR3LPAR2DNM1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143751-A1 INJECTABLE LONG-ACTING ANALGESIC PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院上海药物研究所 2021-07-22 WO claimed
EP-0100910-B1 LUNG SURFACTANT A. Nattermann & Cie. GmbH (DE) 1988-11-02 EP claimed
US-20220185918-A1 AMPHIPHILIC COMPOUND, AND MEDICAL RESIN COMPOSITION AND PHARMACEUTICAL ADDITIVE USING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 2022-06-16 US disclosed
WO-2022050369-A1 LIPOSOME PREPARATION CONTAINING ANTIBACTERIAL DRUG 国立大学法人大阪大学 2022-03-10 WO disclosed
EP-3950735-A1 AMPHIPHILIC COMPOUND, AND RESIN COMPOSITION FOR MEDICAL USE AND DRUG ADDITIVE EACH USING SAME Nippon Shokubai Co., Ltd. (JP) 2022-02-09 EP disclosed
WO-2020203998-A1 AMPHIPHILIC COMPOUND, AND RESIN COMPOSITION FOR MEDICAL USE AND DRUG ADDITIVE EACH USING SAME 株式会社日本触媒 2020-10-08 WO disclosed
US-8367077-B2 Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH, AG (CH) 2013-02-05 US disclosed
CN-101815505-B Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH AG 2012-09-19 CN disclosed
EP-2182923-B1 VIROSOMES COMPRISING HEMAGGLUTININ DERIVED FROM AN INFLUENZA VIRUS PRODUCED IN A CELL LINE, COMPOSITIONS, METHODS OF MANUFACTURING, USE THEREOF PEVION BIOTECH AG (CH) 2012-01-04 EP disclosed
US-20110045057-A1 Virosomes Comprising Hemagglutinin Derived from an Influenza Virus Produced in a Cell Line, Compositions, Methods of Manufacturing, Use Thereof PEVION BIOTECH, AG (CH) 2011-02-24 US disclosed
CN-101815505-A Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH AG 2010-08-25 CN disclosed
EP-2014279-A1 Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof Pevion Biotech AG (CH) 2009-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185918-A1 AMPHIPHILIC COMPOUND, AND MEDICAL RESIN COMPOSITION AND PHARMACEUTICAL ADDITIVE USING THE SAME LIPA, ABHD16A, ABCB11 LPAR1 506/4885LPAR3 1130/4885LPAR2 844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.