Aclonifen

Aclonifen

SCHEMBL7576804

N#Cc1cc(Br)c(O)c(Br)c1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.66

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
TTR P02766 2/20 0.66
ALB P02768 2/20 0.66
TDP1 Q9NUW8 2/20 0.66
THRB P10828 1/20 0.66
MERTK Q12866 1/20 0.43
VCAM1 P19320 2/20 0.40
PDE7A Q13946 2/20 0.38
HPSE Q9Y251 1/20 0.37
F10 P00742 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.36
CTSB P07858 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HTR6 P50406 1/20 0.34
EPAS1 Q99814 1/20 0.34
STK39 Q9UEW8 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL7583158 0.87 TDP1 (0.50) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL7575296 0.85 MEN1 (0.48) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL7582226 0.84 MEN1 (0.47) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL55487 0.81 MEN1 (1.00) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL4894870 0.81 MEN1 (1.00) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL29470834 0.81 MEN1 (1.00) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL2297957 0.75 MEN1 (0.81) MEN1KMT2ATTRALBTDP1
Aclonifen SCHEMBL9711313 0.75 MEN1 (0.85) MEN1KMT2ATTRALBTDP1
SCHEMBL11069815 0.73 MEN1 (0.57) MEN1KMT2ATTRALBTDP1
SCHEMBL11064915 0.72 MEN1 (0.75) MEN1KMT2ATTRALBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.