Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639604 | 0.87 | NPC1 (0.54) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL7584713 | 0.86 | CA1 (0.44) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL1696047 | 0.84 | MDM2 (0.48) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL4856820 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL7584703 | 0.81 | NPC1 (0.53) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL7574221 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL2483521 | 0.81 | FPR2 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL146704 | 0.81 | FPR2 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL2483519 | 0.81 | FPR2 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL7576130 | 0.81 | NPC1 (0.56) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |