SCHEMBL7576873

SCHEMBL7576873

CCCCCCCCCCCCCCCCCC(=O)OCCOc1ccc(C2C(=O)Oc3cccc(C(C)(C)C)c32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.38
S1PR1 P21453 4/20 0.37
S1PR3 Q99500 3/20 0.37
S1PR4 O95977 2/20 0.37
S1PR5 Q9H228 1/20 0.36
CNR2 P34972 2/20 0.35
TLR2 O60603 2/20 0.35
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
ALDH2 P05091 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025325 0.88 DGKA (0.38) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL4447714 0.87 CNR2 (0.40) DGKACNR2ESR1ESR2TP53
SCHEMBL7759240 0.81 CYP3A4 (0.36) SMN1; SMN2ESR1ESR2ALDH2MAOA
SCHEMBL1274016 0.80 KDM4E (0.41) POLBMAPTLMNAESR1TSHR
SCHEMBL6051283 0.80 CNR2 (0.35) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL39389 0.79 DGKA (0.37) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL21176407 0.79 DGKA (0.37) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL984668 0.76 DGKA (0.34) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL6025323 0.76 DGKA (0.38) DGKAS1PR1S1PR3S1PR4S1PR5
SCHEMBL26025226 0.75 CNR2 (0.37) DGKAS1PR1S1PR3S1PR4S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012153260-A1 MIXTURE OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION 3V SIGMA S.P.A. (IT) 2012-11-15 WO disclosed
EP-1238003-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-09-11 EP disclosed
WO-2001034694-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2001-05-17 WO disclosed