Mesotrione

Mesotrione

SCHEMBL7577151

CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.37
VCAM1 P19320 1/20 0.36
THRB P10828 2/20 0.33
MAPT P10636 5/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 3/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulcotrione SCHEMBL7582403 0.92 MAPT (0.34) MAPTLMNAALDH1A1POLBGAA
Mesotrione SCHEMBL7578050 0.91 VCAM1 (0.31) HPDVCAM1
Mesotrione SCHEMBL7584587 0.90 GRM8 (0.32) HPDVCAM1
Mesotrione SCHEMBL7582274 0.89
Mesotrione SCHEMBL7579264 0.86 MEN1 (0.32) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
Sulcotrione SCHEMBL7580663 0.83 MAPT (0.31) MAPTGAA
Sulcotrione SCHEMBL7586033 0.82 GRM4 (0.30)
Sulcotrione SCHEMBL7588690 0.82 GAA (0.30) MAPTGAA
SCHEMBL39177 0.80 MAPT (0.37) MAPTALDH1A1KMT2AHTT
SCHEMBL5467830 0.80 MAPT (0.37) MAPTALDH1A1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPD 7/4885VCAM1 4877/4885THRB 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.