Nicosulfuron

Nicosulfuron

SCHEMBL7577246

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.34
CYP3A4 P08684 4/20 0.32
UGCG Q16739 4/20 0.32
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAF1 P04049 1/20 0.30
THRB P10828 1/20 0.30
FFAR1 O14842 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicosulfuron SCHEMBL7577022 0.95 CDK1 (0.33) CDK1CYP3A4UGCG
Primisulfuron SCHEMBL7577262 0.94 CDK1 (0.32) CDK1
Nicosulfuron SCHEMBL7579161 0.93 CDK1 (0.37) CDK1CYP3A4UGCGLMNAKDM4E
Rimsulfuron SCHEMBL7583534 0.91 PPARG (0.31) CYP3A4UGCGLMNAKDM4EGAA
Nicosulfuron SCHEMBL7588554 0.90 CDK1 (0.30) CDK1
Nicosulfuron SCHEMBL7577828 0.89 CYP3A4 (0.33) CDK1CYP3A4UGCGLMNAKDM4E
Nicosulfuron SCHEMBL7589504 0.89
Primisulfuron SCHEMBL7583664 0.89 CDK1 (0.31) CDK1
Lactofen SCHEMBL7589898 0.89 TDP1 (0.37) CDK1CYP3A4UGCG
Nicosulfuron SCHEMBL7584990 0.87 TDP1 (0.45) CDK1CYP3A4UGCGLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT CDK1 1256/4885CYP3A4 179/4885UGCG 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.