Nicosulfuron

Nicosulfuron

SCHEMBL7579161

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.37
LMNA P02545 2/20 0.35
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
THRB P10828 1/20 0.35
RAF1 P04049 1/20 0.35
CYP3A4 P08684 4/20 0.34
UGCG Q16739 4/20 0.34
MEN1 O00255 1/20 0.33
TTR P02766 1/20 0.33
PPOX P50336 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FFAR1 O14842 1/20 0.33
SCN9A Q15858 1/20 0.32
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7576089 0.93 CDK1 (0.35) CDK1LMNAGAAKDM4EMAPT
Nicosulfuron SCHEMBL7577246 0.93 CDK1 (0.34) CDK1LMNAGAAKDM4EMAPT
Nicosulfuron SCHEMBL7577828 0.92 CYP3A4 (0.33) CDK1LMNAGAAKDM4EMAPT
Nicosulfuron SCHEMBL7576892 0.92 CDK1 (0.32) CDK1LMNAGAAKDM4EMAPT
Flazasulfuron SCHEMBL7578001 0.92 LMNA (0.38) LMNAGAAKDM4EMAPTHPGD
Nicosulfuron SCHEMBL7577022 0.91 CDK1 (0.33) CDK1CYP3A4UGCG
Rimsulfuron SCHEMBL7575973 0.89 LMNA (0.35) LMNAGAAKDM4EMAPTHPGD
Nicosulfuron SCHEMBL7586556 0.89 CDK1 (0.33) CDK1
Primisulfuron SCHEMBL7577262 0.87 CDK1 (0.32) CDK1
SCHEMBL7596990 0.86 LMNA (0.39) CDK1LMNAGAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT CDK1 1256/4885LMNA 3881/4885GAA 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.