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Mesotrione

Mesotrione

SCHEMBL7577265

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1.C[S+](C)C.Cc1nn(-c2cc(NS(C)(=O)=O)c(Cl)cc2Cl)c(=O)n1C(F)F.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PPOX P50336 1/20 0.47
▸ HPD P32754 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesotrione SCHEMBL7578549 0.94 PPOX (0.49) PPOXHPD
Sulfentrazone SCHEMBL7576865 0.93 PPOX (0.50) PPOX
Mesotrione SCHEMBL7584751 0.89 PPOX (0.59) PPOXHPD
Mesotrione SCHEMBL7590310 0.88 PPOX (0.36) PPOX
Sulfentrazone SCHEMBL7577122 0.88 PPOX (0.52) PPOX
Mesotrione SCHEMBL7578140 0.85 PPOX (0.47) PPOXHPD
Carfentrazone-Ethyl SCHEMBL7580658 0.84 — —
Sulfentrazone SCHEMBL7577503 0.84 PPOX (0.66) PPOX
Mesotrione SCHEMBL17942155 0.83 PPOX (0.49) PPOXHPD
Mesotrione SCHEMBL7580768 0.83 PPOX (0.37) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885HPD 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.