Mesotrione

Mesotrione

SCHEMBL7584751

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1.Cc1nn(-c2cc(NS(C)(=O)=O)c(Cl)cc2Cl)c(=O)n1C(F)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.59
HPD P32754 1/20 0.38
ALDH3A1 P30838 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesotrione SCHEMBL17942155 0.92 PPOX (0.49) PPOXHPD
Sulfentrazone SCHEMBL7582341 0.92 PPOX (0.64) PPOX
Mesotrione SCHEMBL7578549 0.91 PPOX (0.49) PPOXHPD
Mesotrione SCHEMBL7578140 0.90 PPOX (0.47) PPOXHPD
Mesotrione SCHEMBL7577265 0.89 PPOX (0.47) PPOXHPD
Mesotrione SCHEMBL7581049 0.85 PPOX (0.43) PPOXALDH1A1
Sulfentrazone SCHEMBL7577122 0.83 PPOX (0.52) PPOX
Sulfentrazone SCHEMBL7589172 0.81 PPOX (0.51) PPOX
Sulfentrazone SCHEMBL7576865 0.81 PPOX (0.50) PPOX
Mesotrione SCHEMBL7580768 0.80 PPOX (0.37) PPOXALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11122805-B2 Herbicidal combination formulations and methods SIPCAM AGRO USA, INC. (US) 2021-09-21 US disclosed
US-20200267979-A1 HERBICIDAL COMBINATION FORMULATIONS AND METHODS SIPCAM AGRO USA, INC. (US) 2020-08-27 US disclosed
EP-3247213-A1 TERNARY HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL BASF Agro B.V. (NL) 2017-11-29 EP disclosed
EP-3244742-A1 HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL AND GLUFOSINATE BASF SE (DE) 2017-11-22 EP disclosed
CN-104255738-B A kind of sugarcane field herbicidal composition and application thereof 河南远见农业科技有限公司 2016-09-07 CN disclosed
WO-2016116531-A1 TERNARY HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL BASF Agro B.V. (NL) 2016-07-28 WO disclosed
WO-2016113334-A1 HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL AND GLUFOSINATE BASF SE (DE) 2016-07-21 WO disclosed
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885HPD 7/4885ALDH3A1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.