Flazasulfuron

Flazasulfuron

SCHEMBL7577284

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
TTR P02766 1/20 0.37
ALB P02768 1/20 0.37
THRB P10828 1/20 0.37
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
GAA P10253 2/20 0.34
KDR P35968 3/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 2/20 0.34
ALOX12 P18054 2/20 0.34
CCR6 P51684 1/20 0.34
PKM P14618 1/20 0.33
ADAMTS5 Q9UNA0 3/20 0.32
KDM4E B2RXH2 2/20 0.31
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flupyrsulfuron SCHEMBL7578529 0.91 KMT2A (0.35) KMT2AMEN1TDP1TTRALB
Flazasulfuron SCHEMBL7586436 0.91 MEN1 (0.45) KMT2AMEN1TDP1TTRALB
Aclonifen SCHEMBL7595067 0.88 KMT2A (0.39) KMT2AMEN1TDP1TTRALB
Flazasulfuron SCHEMBL7584684 0.86 TDP1 (0.45) KMT2AMEN1TDP1TTRNPC1
Flazasulfuron SCHEMBL7579830 0.85 KMT2A (0.38) KMT2AMEN1TDP1TTRNPC1
Sulfosulfuron SCHEMBL7581842 0.85 KMT2A (0.34) KMT2AMEN1TDP1TTRALB
Fomesafen SCHEMBL7585279 0.84 KMT2A (0.41) KMT2AMEN1TDP1TTRTHRB
Flazasulfuron SCHEMBL7589736 0.82 MEN1 (0.39) KMT2AMEN1TDP1TTRTHRB
Chlorsulfuron SCHEMBL7579708 0.81 KMT2A (0.38) KMT2AMEN1TDP1TTRALB
Lactofen SCHEMBL7585539 0.81 MEN1 (0.38) KMT2AMEN1TDP1TTRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.