Flazasulfuron

Flazasulfuron

SCHEMBL7586436

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
ALB P02768 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GAA P10253 1/20 0.40
TBXA2R P21731 5/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
TXNRD1 Q16881 2/20 0.33
PDGFRA P16234 1/20 0.33
KDR P35968 1/20 0.33
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
RAF1 P04049 1/20 0.32
BRAF P15056 1/20 0.32
AXL P30530 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL7577284 0.91 KMT2A (0.37) MEN1TTRALBTHRBKMT2A
Nicosulfuron SCHEMBL7579393 0.87 MEN1 (0.44) MEN1TTRALBTHRBKMT2A
Flupyrsulfuron SCHEMBL7589707 0.86 MEN1 (0.45) MEN1TTRALBTHRBKMT2A
Flazasulfuron SCHEMBL7585892 0.82 TDP1 (0.56) MEN1TTRKMT2ATDP1GAA
Aclonifen SCHEMBL7596875 0.82 MEN1 (0.51) MEN1TTRALBTHRBKMT2A
Flazasulfuron SCHEMBL7580038 0.82 TDP1 (0.54) MEN1TTRKMT2ATDP1GAA
Flupyrsulfuron SCHEMBL7578529 0.81 KMT2A (0.35) MEN1TTRALBTHRBKMT2A
Primisulfuron SCHEMBL7580022 0.81 TDP1 (0.37) MEN1TTRALBTHRBKMT2A
Rimsulfuron SCHEMBL7578104 0.81 MEN1 (0.38) MEN1TTRALBTHRBKMT2A
Primisulfuron SCHEMBL7575653 0.81 CDK1 (0.38) MEN1TTRALBTHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885TTR 1945/4885ALB 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.