Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351613 | 0.76 | KMT2A (0.53) | KMT2AGLO1PSIP1PARP14ALDH1A1 | |
| SCHEMBL7577310 | 0.74 | PTGES2 (0.53) | KMT2AALDH1A1 | |
| SCHEMBL4301369 | 0.72 | CA1 (0.53) | KMT2AALDH1A1KDM4EHPGDCA2 | |
| SCHEMBL10622905 | 0.71 | CA2 (0.61) | PSIP1CA2CA1 | |
| SCHEMBL6566936 | 0.70 | CA1 (0.56) | KMT2AGLO1PARP14ALDH1A1KDM4E | |
| SCHEMBL5594880 | 0.70 | GLO1 (0.48) | KMT2AGLO1PARP14ALDH1A1KDM4E | |
| SCHEMBL7898382 | 0.67 | GLO1 (0.54) | KMT2AGLO1PARP14ALDH1A1KDM4E | |
| SCHEMBL14403271 | 0.67 | ALDH1A1 (0.55) | KMT2AGLO1PARP14ALDH1A1KDM4E | |
| SCHEMBL14803887 | 0.67 | GLO1 (0.50) | KMT2AGLO1ALDH1A1KDM4EHPGD | |
| SCHEMBL4343432 | 0.67 | KMT2A (0.51) | KMT2AGLO1PARP14ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |