SCHEMBL757737

SCHEMBL757737

Cc1cc(C(c2ccc(O)cc2)c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.44
ESR2 Q92731 7/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
PTGS1 P23219 3/20 0.43
PTGS2 P35354 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.40
CYP3A4 P08684 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
AR P10275 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CHRM1 P11229 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1595123 0.93 CA1 (0.48) ESR1ESR2PTGS1PTGS2CA1
SCHEMBL22238284 0.92 ESR1 (0.39) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL8752837 0.88 ESR1 (0.47) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL21241774 0.87 PTGS1 (0.48) PTGS1PTGS2CA1CA2LMNA
SCHEMBL673321 0.86 CA1 (0.55) ESR1ESR2PTGS1PTGS2CA1
SCHEMBL22238296 0.85 PTGS1 (0.42) ESR1ESR2PTGS1PTGS2CA1
SCHEMBL17570373 0.85 PTGS1 (0.59) PTGS1PTGS2CA1CA2LMNA
SCHEMBL22550574 0.83 ESR1 (0.41) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL21241741 0.83 PTGS1 (0.41) ESR1ESR2PTGS1PTGS2CA1
SCHEMBL15134980 0.83 PTGS1 (0.52) PTGS1PTGS2CA1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203783-A2 THICK FILM RESISTS AZ Electronic Materials USA Corp. (US) 2010-07-07 EP claimed
WO-2009040661-A2 THICK FILM RESISTS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-02 WO claimed
US-20090081589-A1 THICK FILM RESISTS MERCK PATENT GMBH (DE) 2009-03-26 US claimed
EP-0591984-B1 Resin composition for aqueous paint KANSAI PAINT CO LTD (JP) 1997-07-09 EP claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-20260050215-A1 MATERIAL FOR FORMING SUPERFINE PATTERN, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN TREATMENT COMPOSITION AND FORMATION METHOD OF SUPERFINE PATTERN Advanced Echem Materials Company Limited (TW) 2026-02-19 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12497558-B2 Colour change composition and compounds THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-12-16 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
US-12297357-B2 Temperature-sensitive indicator THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-05-13 US disclosed
EP-0489395-B1 Dyed mixed knit fabric and method for its manufacture TOYO BOSEKI (JP) 1995-09-27 EP disclosed
EP-0672952-A1 Positive photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1995-09-20 EP disclosed
US-5434031-A Positive-working naphthoquinone diazide photoresist composition containing specific hydroxy compound additive TOKYO OHKA KOGYO CO., LTD. (JP) 1995-07-18 US disclosed
EP-0658807-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1995-06-21 EP disclosed
US-5407748-A Resin composition for aqueous paint KANSAI PAINT CO., LTD. (JP) 1995-04-18 US disclosed
EP-0644460-A1 Positive working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1995-03-22 EP disclosed
US-5332647-A Photosensitive resins for elements TOKYO OHKA KOGYO CO., LTD. (JP) 1994-07-26 US disclosed
EP-0489395-A1 Dyed mixed knit fabric and method for its manufacture Toyo Boseki Kabushiki Kaisha (JP) 1992-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297357-B2 Temperature-sensitive indicator NCS1, TREH, NEFM ESR1 236/4885ESR2 1581/4885PDCD1 1095/4885
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB ESR1 4366/4885ESR2 3067/4885PDCD1 4031/4885
US-12497558-B2 Colour change composition and compounds C5, C9, C3AR1 ESR1 20/4885ESR2 77/4885PDCD1 1278/4885
US-20260050215-A1 MATERIAL FOR FORMING SUPERFINE PATTERN, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN TREATMENT COMPOSITION AND FORMATION METHOD OF SUPERFINE PATTERN SEM1, ASH2L, RAD51 ESR1 1140/4885ESR2 2362/4885PDCD1 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.