Bifenox

Bifenox

SCHEMBL7577487

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].CP(=O)(O)CCC(N)C(=O)O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.58
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TTR P02766 2/20 0.46
ALB P02768 1/20 0.46
THRB P10828 1/20 0.46
LMNA P02545 2/20 0.41
GRM8 O00222 10/20 0.40
GRM4 Q14833 10/20 0.40
GRM6 O15303 6/20 0.40
PPOX P50336 1/20 0.38
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
GRM7 Q14831 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7582508 0.85 TDP1 (0.59) TDP1MEN1KMT2ATTRALB
Bifenox SCHEMBL7576616 0.84 TDP1 (0.61) TDP1MEN1KMT2ATTRALB
Bifenox SCHEMBL7586481 0.84 TDP1 (0.57) TDP1MEN1KMT2ATTRGRM8
Bifenox SCHEMBL7582699 0.82 TDP1 (0.55) TDP1MEN1KMT2ATTRGRM8
Lactofen SCHEMBL7582649 0.82 TDP1 (0.47) TDP1MEN1KMT2ATTRALB
Bifenox SCHEMBL7577363 0.81 TDP1 (0.57) TDP1MEN1KMT2ATTRALB
Aclonifen SCHEMBL7585569 0.81 MEN1 (0.47) TDP1MEN1KMT2ATTRALB
Bifenox SCHEMBL7583517 0.81 TDP1 (0.51) TDP1MEN1KMT2ATTRLMNA
Bifenox SCHEMBL7580827 0.81 TDP1 (0.49) TDP1MEN1KMT2ATTRLMNA
Bifenox SCHEMBL7578797 0.81 TDP1 (0.49) TDP1MEN1KMT2ATTRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.