Aclonifen

Aclonifen

SCHEMBL7585569

CP(=O)(O)CCC(N)C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
TTR P02766 2/20 0.47
PPOX P50336 1/20 0.47
ALB P02768 1/20 0.41
THRB P10828 1/20 0.41
FFAR1 O14842 2/20 0.38
GRM8 O00222 7/20 0.36
GRM4 Q14833 7/20 0.36
GRM6 O15303 6/20 0.36
MAPT P10636 3/20 0.34
LMNA P02545 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
POLB P06746 2/20 0.34
CCR6 P51684 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7582649 0.92 TDP1 (0.47) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7582508 0.90 TDP1 (0.59) MEN1KMT2ATDP1TTRPPOX
Aclonifen SCHEMBL7587392 0.90 TDP1 (0.57) MEN1KMT2ATDP1TTRPPOX
Glufosinate SCHEMBL7584658 0.88 FFAR1 (0.46) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7582566 0.87 MEN1 (0.46) MEN1KMT2ATDP1TTRPPOX
Aclonifen SCHEMBL7589220 0.86 MEN1 (0.47) MEN1KMT2ATDP1TTRPPOX
Aclonifen SCHEMBL7578996 0.84 MEN1 (0.45) MEN1KMT2ATDP1TTRPPOX
Lactofen SCHEMBL21658823 0.83 TDP1 (0.53) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7585173 0.83 TDP1 (0.70) MEN1KMT2ATDP1TTRPPOX
Bifenox SCHEMBL7577487 0.81 TDP1 (0.58) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.