Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585358 | 0.88 | FPR2 (0.49) | FPR2L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL7574119 | 0.85 | ALDH1A1 (0.56) | FPR2L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7582089 | 0.83 | FPR2 (0.46) | FPR2L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL18360852 | 0.80 | ALDH1A1 (0.57) | FPR2L3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL7583413 | 0.77 | FPR2 (0.67) | FPR2ALDH1A1KMT2AMEN1S1PR3 | |
| SCHEMBL7576266 | 0.76 | CA1 (0.51) | FPR2POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL7574039 | 0.75 | FPR2 (0.47) | FPR2ALDH1A1LMNACA1CA2 | |
| SCHEMBL839473 | 0.74 | MEN1 (0.50) | FPR2L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11203574 | 0.74 | KMT2A (0.51) | FPR2ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9298164 | 0.73 | FPR2 (0.47) | FPR2ALDH1A1KMT2AMEN1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |