Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577631 | 0.85 | FPR2 (0.49) | ALDH1A1L3MBTL1LMNANPC1SMN1; SMN2 | |
| SCHEMBL7582068 | 0.85 | ULK1 (0.54) | ALDH1A1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL839473 | 0.84 | MEN1 (0.50) | ALDH1A1L3MBTL1LMNANPC1SMN1; SMN2 | |
| SCHEMBL14938214 | 0.83 | LMNA (0.63) | ALDH1A1L3MBTL1LMNANPC1SMN1; SMN2 | |
| SCHEMBL14948916 | 0.83 | LMNA (0.63) | ALDH1A1L3MBTL1LMNANPC1SMN1; SMN2 | |
| SCHEMBL7577550 | 0.82 | PPARG (0.51) | ALDH1A1L3MBTL1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL7578428 | 0.82 | MAP2K1 (0.44) | ALDH1A1L3MBTL1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL7585358 | 0.82 | FPR2 (0.49) | ALDH1A1L3MBTL1LMNANPC1SMN1; SMN2 | |
| SCHEMBL2484664 | 0.81 | GAA (0.50) | ALDH1A1LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL13241014 | 0.81 | GAA (0.50) | ALDH1A1LMNANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |