Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61027 | 0.84 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL29843943 | 0.84 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL5981385 | 0.84 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL6671922 | 0.84 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL8971825 | 0.81 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL31530502 | 0.81 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL6672427 | 0.81 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL6063638 | 0.81 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7577803 | 0.80 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL30745575 | 0.80 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114556-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5962359-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0723971-A2 | Metallocenes and their use as catalyst component | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |