Flupyrsulfuron

Flupyrsulfuron

SCHEMBL7578385

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2nc(C(F)(F)F)ccc2C(=O)O)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
HSP90AA1 P07900 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TTR P02766 1/20 0.33
PPOX P50336 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 2/20 0.32
LMNA P02545 2/20 0.32
HPGD P15428 1/20 0.32
PTGDR2 Q9Y5Y4 2/20 0.31
PKM P14618 1/20 0.31
PYGL P06737 1/20 0.30
PYGM P11217 1/20 0.30
SLC40A1 Q9NP59 1/20 0.30
THRB P10828 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL7578330 0.92 KDM4E (0.34) MEN1KMT2AKDM4EMAPTHSP90AA1
SCHEMBL7597724 0.90 KDM4E (0.34) MEN1KMT2AKDM4EMAPTHSP90AA1
Lactofen SCHEMBL7580461 0.90 MEN1 (0.39) MEN1KMT2AMAPTNPSR1L3MBTL1
Flupyrsulfuron SCHEMBL7580422 0.90 KMT2A (0.40) MEN1KMT2AKDM4EMAPTTTR
Flupyrsulfuron SCHEMBL7582658 0.89 KMT2A (0.46) MEN1KMT2AKDM4EMAPTHSP90AA1
Flupyrsulfuron SCHEMBL7576791 0.87 KMT2A (0.41) MEN1KMT2AKDM4EMAPTHSP90AA1
Flupyrsulfuron SCHEMBL7582327 0.86 MEN1 (0.42) MEN1KMT2AKDM4EMAPTHSP90AA1
Flupyrsulfuron SCHEMBL7582081 0.85 MEN1 (0.40) MEN1KMT2AKDM4EMAPTHSP90AA1
SCHEMBL7585257 0.84 KDM4E (0.32) MEN1KMT2AKDM4EMAPTHSP90AA1
Flupyrsulfuron SCHEMBL7584020 0.84 TDP1 (0.43) MEN1KMT2AKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.