Flupyrsulfuron

Flupyrsulfuron

SCHEMBL7580422

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2nc(C(F)(F)F)ccc2C(=O)O)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 2/20 0.39
LMNA P02545 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 1/20 0.37
FFAR1 O14842 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CDK1 P06493 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.33
SORT1 Q99523 2/20 0.32
PYGL P06737 1/20 0.32
PYGM P11217 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flupyrsulfuron SCHEMBL7578385 0.90 MEN1 (0.33) KMT2AMEN1TTRPPOXTDP1
SCHEMBL7596990 0.88 LMNA (0.39) KMT2AMEN1TTRPPOXTDP1
Flazasulfuron SCHEMBL7578001 0.87 LMNA (0.38) KMT2AMEN1TTRPPOXTDP1
Lactofen SCHEMBL7579263 0.87 KMT2A (0.47) KMT2AMEN1TTRPPOXTDP1
SCHEMBL7589011 0.86 MEN1 (0.37) KMT2AMEN1TTRPPOXTDP1
Nicosulfuron SCHEMBL7579161 0.86 CDK1 (0.37) KMT2AMEN1TTRPPOXTDP1
Flupyrsulfuron SCHEMBL7581127 0.86 TDP1 (0.59) KMT2AMEN1TTRPPOXTDP1
Halosulfuron SCHEMBL7580413 0.85 LMNA (0.36) KMT2AMEN1TTRPPOXTDP1
Rimsulfuron SCHEMBL7575973 0.85 LMNA (0.35) KMT2AMEN1TTRPPOXTDP1
SCHEMBL7579452 0.84 MEN1 (0.38) KMT2AMEN1TTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.