Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | BLK | P51451 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.39 |
| ▸ | DAPK2 | Q9UIK4 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546181 | 0.81 | TOP1 (0.49) | MAOAMAOBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7545914 | 0.79 | TYR (0.49) | STK17BMAOAMAOBMAPTALDH1A1 | |
| SCHEMBL6670897 | 0.76 | STK17B (0.47) | STK17BAURKAGSK3BELANEMAOA | |
| SCHEMBL6671599 | 0.76 | MAOA (0.32) | STK17BMAOAMAOBALDH1A1TDP1 | |
| SCHEMBL7567696 | 0.71 | STK17B (0.42) | STK17BAURKAGSK3BELANEMAOA | |
| SCHEMBL7552791 | 0.70 | MAOB (0.54) | MAOAMAOBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7549906 | 0.70 | TYR (0.51) | STK17BAURKADAPK3GSK3BBLK | |
| SCHEMBL42261 | 0.64 | MAOA (0.53) | TGM2MAOAMAOBMAPTALDH1A1 | |
| SCHEMBL30950420 | 0.64 | MAOA (0.53) | TGM2MAOAMAOBMAPTALDH1A1 | |
| SCHEMBL30970619 | 0.63 | MAOA (0.56) | TGM2MAOAMAOBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977747-B1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT FINANCE BVI LTD (VG) | 2002-06-12 | — | — | EP | disclosed |
| EP-0977747-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998039319-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| US-5726295-A | Photoactive coumarin derivatives | HOECHST CELANESE CORP. (US) | 1998-03-10 | — | — | US | disclosed |