SCHEMBL757869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10121207	0.92	MRGPRX4 (0.52)	SLC6A2SLC6A4KCNH2SLC6A3ROCK2
	SCHEMBL765629	0.87	ST14 (0.50)	SLC6A2SLC6A4KCNH2SLC6A3ROCK2
	SCHEMBL12238998	0.87	ROCK2 (0.51)	SLC6A4KCNH2ROCK2ROCK1AKT1
	SCHEMBL765563	0.82	SLC6A2 (0.47)	SLC6A2SLC6A4SLC6A3ROCK2ROCK1
	SCHEMBL23380132	0.81	L3MBTL1 (0.44)	SLC6A2SLC6A4KCNH2SLC6A3MRGPRX4
	SCHEMBL14662168	0.78	ROCK2 (0.55)	SLC6A4ROCK2ROCK1AKT1RPS6KA1
	SCHEMBL12239000	0.78	ROCK2 (0.52)	SLC6A4KCNH2ROCK2ROCK1PNMT
	SCHEMBL5503983	0.77	SLC6A4 (0.50)	SLC6A2SLC6A4KCNH2SLC6A3PPARG
	SCHEMBL921313	0.76	ROCK2 (0.50)	SLC6A4ROCK2ROCK1AKT1RPS6KA1
	SCHEMBL29729049	0.74	KDM4E (0.53)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.