SCHEMBL757891

SCHEMBL757891

COc1c2ccccc2c(OC)c2cc(C)c(C)cc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.71
ALDH1A1 P00352 4/20 0.71
MAPK1 P28482 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
POLB P06746 1/20 0.50
MAPT P10636 2/20 0.43
MCL1 Q07820 1/20 0.43
ATM Q13315 1/20 0.43
CYP1A2 P05177 5/20 0.42
CYP2C9 P11712 1/20 0.40
IDO1 P14902 1/20 0.40
CYP2C19 P33261 1/20 0.39
HTT P42858 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ERN1 O75460 1/20 0.37
CYP2A6 P11509 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366257 1.00 KDM4E (0.71) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL29366129 0.84 ALDH1A1 (1.00) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL52405 0.84 ALDH1A1 (1.00) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL29364382 0.82 KDM4E (0.65) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL2228418 0.82 KDM4E (0.65) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
Iodide SCHEMBL5967814 0.82 ALDH1A1 (0.94) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL4646489 0.81 KDM4E (0.58) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL30660758 0.80 KDM4E (0.79) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL755681 0.80 KDM4E (0.79) KDM4EALDH1A1MAPK1SMN1; SMN2POLB
SCHEMBL27861347 0.80 ALDH1A1 (0.50) KDM4EALDH1A1MAPK1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
EP-4516394-A2 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2025-03-05 EP disclosed
EP-4481059-A2 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2024-12-25 EP disclosed
EP-4405094-B1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-12-18 EP disclosed
EP-4271511-B1 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-10-09 EP disclosed
US-20240167077-A1 COVALENT ATTACHMENT OF SPLINT OLIGONUCLEOTIDES FOR MOLECULAR ARRAY GENERATION USING LIGATION 10X GENOMICS, INC. (US) 2024-05-23 US disclosed
US-20240076656-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2024-03-07 US disclosed
US-20240060127-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. 2024-02-22 US disclosed
WO-2024006798-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
WO-2024006827-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
EP-0846681-B1 NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD NIPPON SODA CO (JP) 2003-12-03 EP disclosed
US-6558871-B1 Photopolymerization initiator comprising at least one of diaryliodonium salt NIPPON SODA CO. LTD. (JP) 2003-05-06 US disclosed
EP-1201638-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2002-05-02 EP disclosed
US-6313188-B1 USED AS CATALYSTS FOR CATIONIC PHOTOPOLYMERIZATION NIPPON SODA CO., LTD. (JP) 2001-11-06 US disclosed
EP-1106639-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2001-06-13 EP disclosed
US-6093753-A CURABLE COMPOSITION COMPRISING A CATIONIC POLYMERIZABLE COMPOUND WHICH IS AN ALICYCLIC EPOXY COMPOUND OR A VINYL ETHER COMPOUND AND A CATIONIC POLYMERIZATION INITIATOR; PAINTS, ADHESIVES, INKS, PHOTORESISTS NIPPON SODA CO., LTD. (JP) 2000-07-25 US disclosed
US-6068962-A NOVOLAK RESIN AS AN ALKALI-SOLUBLE COMPONENT; QUINONEDIAZIDE; ACID GENERATOR; ANTHRACENE DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-30 US disclosed
EP-0927726-A1 PHOTOCATALYTIC COMPOSITION NIPPON SODA CO., LTD. (JP) 1999-07-07 EP disclosed
EP-0846681-A1 NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD NIPPON SODA CO., LTD. (JP) 1998-06-10 EP disclosed
EP-0831371-A2 Positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 KDM4E 1169/4885ALDH1A1 189/4885MAPK1 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.