SCHEMBL4646489

SCHEMBL4646489

COc1c2ccccc2c(OC)c2c1cc(C)c1ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 1/20 0.58
POLB P06746 1/20 0.47
MCL1 Q07820 1/20 0.41
CYP1A2 P05177 3/20 0.39
CYP2A6 P11509 1/20 0.39
ERN1 O75460 1/20 0.39
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.38
ATM Q13315 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366257 0.81 KDM4E (0.71) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL757891 0.81 KDM4E (0.71) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL146384 0.79 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL8858056 0.76 KDM4E (0.47) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL401290 0.76 KDM4E (0.56) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL1334760 0.76 ALDH1A1 (0.62) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL29366129 0.76 ALDH1A1 (1.00) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL52405 0.76 ALDH1A1 (1.00) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
Iodide SCHEMBL5967814 0.73 ALDH1A1 (0.94) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL1618726 0.73 ALDH1A1 (0.58) KDM4EALDH1A1SMN1; SMN2MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-7365106-B2 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2008-04-29 US disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed