Oxyfluorfen

Oxyfluorfen

SCHEMBL7579084

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1.C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
PTGDR2 Q9Y5Y4 2/20 0.35
FFAR1 O14842 1/20 0.33
ALDH1A1 P00352 4/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32
KCNQ3 O43525 2/20 0.32
KCNQ2 O43526 2/20 0.32
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7579249 0.97 MEN1 (0.41) HPDMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7578170 0.94 HPD (0.44) HPDMEN1KMT2ATDP1TTR
Acifluorfen SCHEMBL7585981 0.93 TDP1 (0.51) HPDMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7587495 0.91 MEN1 (0.43) HPDMEN1KMT2ATDP1TTR
Mesotrione SCHEMBL7579020 0.90 TDP1 (0.41) HPDMEN1KMT2ATDP1TTR
Acifluorfen SCHEMBL7579292 0.89 TDP1 (0.51) HPDMEN1KMT2ATDP1TTR
Lactofen SCHEMBL7575862 0.89 TDP1 (0.40) HPDMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7577853 0.89 HPD (0.53) HPDMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7585975 0.88 HPD (0.32) HPDMEN1KMT2ATDP1TTR
Mesotrione SCHEMBL7577903 0.88 HPD (0.40) HPDMEN1KMT2ATDP1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPD 7/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.