Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15286598 | 0.84 | MAPT (0.53) | TAAR1MEN1ALDH1A1KMT2ACHRM5 | |
| SCHEMBL7581521 | 0.80 | ALDH1A1 (0.53) | ALDH1A1NQO2MAPTKDM4ERAB9A | |
| SCHEMBL22791460 | 0.80 | TAAR1 (0.57) | TAAR1MEN1ALDH1A1KMT2ACHRM5 | |
| SCHEMBL7572617 | 0.78 | TP53 (0.46) | MEN1ALDH1A1KMT2ARELAMAPT | |
| SCHEMBL14198012 | 0.75 | CHRM5 (0.58) | TAAR1MEN1ALDH1A1KMT2ACHRM5 | |
| SCHEMBL9416087 | 0.75 | TAAR1 (0.53) | TAAR1MEN1ALDH1A1KMT2ACHRM5 | |
| SCHEMBL19901437 | 0.75 | MEN1 (0.54) | TAAR1MEN1ALDH1A1KMT2ACHRM5 | |
| SCHEMBL7572362 | 0.75 | MAOB (0.49) | CHRM5NQO2MAPTNFE2L2NPC1 | |
| SCHEMBL7575017 | 0.75 | GRIN1 (0.47) | MEN1ALDH1A1KMT2ACHRM5MAPT | |
| SCHEMBL10689025 | 0.74 | MEN1 (0.64) | TAAR1MEN1ALDH1A1KMT2ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |