Glyphosate

Glyphosate

SCHEMBL7579400

CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.34
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL7578495 0.95 FFAR1 (0.32) FFAR1
SCHEMBL7581631 0.93 FFAR1 (0.37) FFAR1LMNAKDM4EGAAMAPT
Glufosinate SCHEMBL7576698 0.90 FFAR1 (0.33) FFAR1LMNAKDM4EGAAMAPT
Lactofen SCHEMBL7581359 0.89 TDP1 (0.38) FFAR1
Lactofen SCHEMBL7577327 0.85 TDP1 (0.36)
Fomesafen SCHEMBL7586136 0.84 TDP1 (0.40) FFAR1
Oxyfluorfen SCHEMBL7585093 0.84 MEN1 (0.37) FFAR1LMNAGAAMAPT
Acifluorfen SCHEMBL7580007 0.82 TDP1 (0.44) FFAR1
Glyphosate SCHEMBL7586363 0.81
Lactofen SCHEMBL7580953 0.81 KMT2A (0.41) FFAR1LMNAKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885LMNA 3881/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.