Fomesafen

Fomesafen

SCHEMBL7586136

CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1.CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].O=C(O)CNCP(=O)(O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7577507 0.96 TDP1 (0.38) TDP1KMT2AMEN1TTRPPOX
Fomesafen SCHEMBL7585363 0.93 KMT2A (0.44) TDP1KMT2AMEN1TTRPPOX
Oxyfluorfen SCHEMBL7585093 0.90 MEN1 (0.37) TDP1KMT2AMEN1TTRPPOX
Acifluorfen SCHEMBL7580007 0.89 TDP1 (0.44) TDP1KMT2AMEN1TTRPPOX
Fomesafen SCHEMBL7583706 0.89 TDP1 (0.38) TDP1KMT2AMEN1TTRPPOX
Lactofen SCHEMBL7581359 0.88 TDP1 (0.38) TDP1KMT2AMEN1TTRPPOX
Bifenox SCHEMBL7587112 0.87 TDP1 (0.47) TDP1KMT2AMEN1TTRPPOX
Acifluorfen SCHEMBL7582284 0.87 KMT2A (0.54) TDP1KMT2AMEN1TTRPPOX
Glyphosate SCHEMBL7582613 0.86 KMT2A (0.37) TDP1KMT2AMEN1TTRPPOX
Oxyfluorfen SCHEMBL7585833 0.86 MEN1 (0.35) TDP1KMT2AMEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885KMT2A 2099/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.