Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 12/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.35 |
| ▸ | DRD4 | P21917 | 7/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730400 | 0.94 | ADRA1A (0.47) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| SCHEMBL6732872 | 0.85 | ADRA1A (0.48) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| SCHEMBL8554719 | 0.76 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| SCHEMBL7796529 | 0.73 | ADRA1A (0.54) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| SCHEMBL6197410 | 0.72 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL6200207 | 0.72 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| Cadaverine Tartrate SCHEMBL8136242 | 0.71 | ADRA1A (0.52) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9055621 | 0.69 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL6787204 | 0.69 | ADRA1A (0.58) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7640674 | 0.68 | ADRA1A (0.59) | ADRA1AADRA1DADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1139972-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1139972-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037026-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-06-29 | — | — | WO | disclosed |