Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071233 | 0.84 | TDP1 (0.61) | GPR35TDP1ERN1TSHRALDH1A1 | |
| SCHEMBL1970696 | 0.78 | TDP1 (0.54) | GPR35TDP1ERN1TSHRALDH1A1 | |
| SCHEMBL6280266 | 0.78 | GPR35 (0.67) | GPR35TDP1ERN1CTSBCXCR2 | |
| SCHEMBL70167 | 0.78 | GPR35 (0.78) | GPR35TDP1ERN1CTSBCXCR2 | |
| Catechol SCHEMBL28052795 | 0.78 | GPR35 (0.65) | GPR35TDP1ERN1CTSBCXCR2 | |
| Nitrophenolate SCHEMBL29360402 | 0.78 | GPR35 (0.65) | GPR35TDP1CTSBCXCR2TSHR | |
| Nitrophenolate SCHEMBL26026 | 0.78 | GPR35 (0.65) | GPR35TDP1CTSBCXCR2TSHR | |
| Nitrophenolate SCHEMBL28029048 | 0.78 | GPR35 (0.65) | GPR35TDP1CTSBCXCR2TSHR | |
| SCHEMBL29516730 | 0.77 | GPR35 (1.00) | GPR35TDP1ERN1CTSBCXCR2 | |
| SCHEMBL16979 | 0.77 | GPR35 (1.00) | GPR35TDP1ERN1CTSBCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | claimed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | claimed |
| EP-0905124-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-0918050-B1 | Bis-o-amino(thio)phenols and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | claimed |
| EP-0918050-A1 | Bis-o-amino(thio)phenols and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-05-26 | — | — | EP | claimed |
| EP-0905124-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | claimed |
| EP-0905123-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | claimed |
| JP-11158128-A | — | — | None | — | — | JP | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| EP-0905121-B1 | o-nitro(thio)phenol compounds and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | disclosed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-3987050-A | SUBSTITUTED PYRIDINYLALKOXY-, PYRIDINYLALKYLSULFONYL AND PYRIDINYLALKYLTHIO-PHENYL-LOWER-ALKANAMIDES | THE DOW CHEMICAL COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3962265-A | H'-(4-((6-CHLORO-2-PYRIDINYL)OXY)PHENYL)-N-METHYL-N-(1-METHYL-2-PROPYNYL)UREA | THE DOW CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3947437-A | Substituted pyridazinyloxy(thio)phenyl ureas and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3940392-A | Certain pyrazinyloxyphenyl urea compound | THE DOW CHEMICAL COMPANY (US) | 1976-02-24 | — | — | US | disclosed |
| US-3931200-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931201-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | TPMT, PAH, AADAT | GPR35 2961/4885TDP1 3548/4885ERN1 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.